Who's Holdin': Guestbook
ABClex
November 29, 2008
It encompasses a range of health care practices evolved to maintain and restore health by the prevention and treatment of illness.
Contemporary medicine applies health science, biomedical research, and medical technology to diagnose and treat injury and disease, typically through medication, surgery, or some other form of therapy.
The word medicine is derived from the Latin ars medicina, meaning the art of healing.
Though medical technology and clinical expertise are pivotal to contemporary medicine, successful face-to-face relief of actual suffering continues to require the application of ordinary human feeling and compassion, known in English as bedside manner.
As science and technology developed, medicine became more reliant upon medications. Pharmacology developed from herbalism and many drugs are still derived from plants (atropine, ephedrine, warfarin, aspirin, digoxin, vinca alkaloids, taxol, hyoscine, etc). The first of these was arsphenamine / Salvarsan discovered by Paul Ehrlich in 1908 after he observed that bacteria took up toxic dyes that human cells did not. Vaccines were discovered by Edward Jenner and Louis Pasteur. The first major class of antibiotics was the sulfa drugs, derived by French chemists originally from azo dyes. This has become increasingly sophisticated; modern biotechnology allows drugs targeted towards specific physiological processes to be developed, sometimes designed for compatibility with the body to reduce side-effects. Genomics and knowledge of human genetics is having some influence on medicine, as the causative genes of most monogenic genetic disorders have now been identified, and the development of techniques in molecular biology and genetics are influencing medical technology, practice and decision-making.
AddonS^
Sahachiro Hata discovered the anti-syphilitic activity of this compound in 1908 in the laboratory of Paul Ehrlich, during a survey of hundreds of newly synthesized organic arsenical compounds. Ehrlich had theorized that by screening many compounds a drug could be discovered with anti-microbial activity. Ehrlich's team began their search for such a "magic bullet" among chemical derivatives of the dangerously toxic drug atoxyl. This was the first organized team effort to optimize the biological activity of a lead compound through systematic chemical modifications, the basis for nearly all modern pharmaceutical research.
Arsphenamine was marketed under the trade name Salvarsan in 1910. It was also called 606, because it was the 606th compound synthesized for testing Germany it was the practice to designate compounds by their development number. Another compound known commonly in Germany by its number is Parathion, which was the 605th compound to be developed in search for insecticide. It is commonly known as E605 (E stands for Entwicklungsnummer (German for "development number")]. Salvarsan was the first organic anti-syphillitic, and a great improvement over the inorganic mercury compounds that had been used previously. A more soluble (but slightly less effective) arsenical compound, Neosalvarsan, (neoarsphenamine), became available in 1912. These arsenical compounds came with considerable risk of side effects, and they were supplanted as treatments for syphilis in the 1940s by penicillin.
Alithea
November 4, 2008
Have A Very Nice Thanksgiving!!!!!!!!
I'm really thankful for Who's Holdin'.
Keep making great music........
Hang Loose!
Alithea
October 31, 2008
HaVe A RoCkIn' HaLlOwEeN...........
Charles r Rendon
September 9, 2008
Hey Fender guitar tattoo guy, bring me the head of Barry Manilow and I'll keep quiet about black licorice in Colombia. I'ts NOT smokeable!!
Alithea
May 5, 2008
Just wanted to let you guys know you have
my support, and I voted for all of you..
Ian you will always be #1.
Nicole Johnson
March 31, 2008
Great show saturday!! I tried to be added as a friend on myspace, but it won't let me.
-Nicole
February 12, 2008
Had so much fun listening, watching, and dancing to you last saturday at henflings. Thanks for the entertainment!
layla
December 29, 2007
seriously?
NasilaNog
October 7, 2007
Excellent!
Alithea a.k.a. Lee
July 29, 2007
I finally came out Saturday to see you rock out. You guys are awesome.. Keep up
the great sound.
hang loose
Cassie Wilson
June 19, 2007
Hey!! Matt you rock!!
Hilary A (aka Big Sis)
June 7, 2007
Love ya Bro keep on playing
Marcie Higgins - used to be Johnson
June 5, 2007
You guys still ROCK!!!!!!!!
karen
February 23, 2007
LOVE the intensity of new song!!!! hope to hear it in the clubs soon
Curtis Olson
December 24, 2006
yo, sounds great! Love the original sound and great to see you guys still rocking it.
Alithea
October 7, 2006
Love the new music. I'm glad you have another CD-I bought my copy today. Keep
on Rockin'............
Peace out
Mike
September 25, 2006
You guys are the best. Love the music
Andrea
September 24, 2006
Rock on!!!
D.J. Dougherty
August 31, 2006
What is up!!!! you rock stars!!the cd ROCKS!!!! call me ....lets do some pix
peace out D.J.
Jessi S.
August 10, 2006
This is awesome you guys finaly got a cool page up!
Hope to see you all soon!
Huggs, Jessi